Phosphazene-catalyzed intramolecular cyclization of nitrogen-tethered alkynyl esters.
نویسندگان
چکیده
Intramolecular cyclization of nitrogen-tethered alkynyl esters catalyzed by phosphazene organosuperbases P2-tBu and P4-tBu was investigated. Both acyclic and cyclic substrates underwent 5-exo-dig and 5-endo-dig cyclization. This reaction is a rare example of the intramolecular addition of enolates of simple esters to alkynes.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 87 شماره
صفحات -
تاریخ انتشار 2013